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Login or Sign Up. Hi, I have been taking this benzodiazepine Klonopin for the past 10 years and until recently, I am suffering night time acid reflux every night since 2 years ago. I have tried PPI's, H2 blockers, antacids, and natural remedies with no success. I have read an article some where on the web that said that benzodiazepine may relax the Onset and peak of clonazepam muscle so the stomach acid will easily flow back alprazolam benefits for heartburn the esophagus causing heartburn when you lie down flat or sleeping on the bed. Do any of alprazolam benefits for heartburn taking this class of drug called benzodiazepine that is used for anxiety and sleep experience night time acid reflux like me? My doctor told me to taper off the Klonopin and it may help with my acid reflux at night, but I am not sure if alprazolam benefits for heartburn works or not. Has any of you ever tried to taper off the benzo and were able to stop the acid reflux at night? Hi yota, Yes, benzodiazepines have the potential to relax the LES.

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