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Pain management is a high priority for patients with rheumatoid arthritis RA. Muscle relaxants include drugs that reduce muscle spasm for example benzodiazepines such as diazepam Valiumalprazolam Xanaxlorazepam Ativan and non-benzodiazepines such as metaxalone Skelaxin or a combination of paracetamol and orphenadrine Muscol and drugs that prevent increased muscle tone baclofen and dantrolene. Despite a paucity of evidence supporting their use, antispasmodic and antispasticity muscle relaxants have gained widespread clinical acceptance as adjuvants in the management muscle relaxer patients with chronic musculoskeletal pain. The aim of this review was to determine the efficacy and safety of muscle relaxants in pain management in acne treatment accutane uk with RA. The lithium and lexapro combination relaxants that were included in this review are the antispasmodic mix alprazolam, bromazepam, chlordiazepoxide,cinolazepam, clonazepam, cloxazolam, clorazepate, diazepam, estazolam, flunitrazepam, flurazepam, flutoprazepam, halazepam, ketazolam, loprazolam, lorazepam, lormetazepam, medazepam, midazolam, nimetazepam, nitrazepam, nordazepam, oxazepam, pinazepam, prazepam, does adderall xr cause anxiety and depression, temazepam, tetrazepam, triazolamantispasmodic non-benzodiazepines cyclobenzaprine, carisoprodol, chlorzoxazone, meprobamate, methocarbamol, metaxalone, orphenadrine, tizanidine and zopicloneand antispasticity drugs baclofen and dantrolene sodium. We included randomised controlled trials which compared a muscle relaxant to another therapy active, including non-pharmacological therapies, or placebo in adult patients with RA and that reported at least one clinically relevant outcome. Two blinded review authors independently extracted data and assessed the risk of bias in the trials. Meta-analyses were used to examine the efficacy of muscle muscle relaxer on pain, depression, sleep and function, as well as their safety. Six trials participants were included in this review. All trials were xanax with at high risk of bias.

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