Most antidepressant side effects aren't dangerous, but they can be bothersome. Here's what to do. Antidepressants can cause unpleasant side effects.

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When depression symptoms improve after starting an antidepressant, many people need to continue taking medication long term to prevent symptoms from returning. However, in some people, a particular antidepressant may simply stop working over time. Doctors don't fully understand what causes the so-called "poop-out" effect or antidepressant tolerance — known as tachyphylaxis will or why it occurs in some people and not in others. In most cases, depression symptoms get better with adjustments to medication.

Your doctor may recommend that you change the dose of your current antidepressant, change to another antidepressant or add another antidepressant or other type of medication to your current treatment. Psychological counseling psychotherapy also may help. Because "doesnt work" are so many reasons depression treatment can stop working, you may need to see a medical doctor who specializes in diagnosing and treating mental illness psychiatrist to figure out the best course of work what. Mayo Clinic does not endorse companies or products.

Advertising revenue supports our not-for-profit mission. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. Mayo Clinic is a nonprofit organization and proceeds from Web advertising help support our mission. Mayo Clinic does valium tired for days endorse any of the will party products and services advertised.

A single copy lexapro these materials may be reprinted for noncommercial personal use only. This will does not have tramadol and paracetamol English version. This content does not have an Arabic version. Can they stop working? Free E-newsletter Subscribe to Housecall Our general interest e-newsletter keeps you up to date on a wide variety of health topics.

I've taken fluoxetine Prozac for several years. But recently, the medication doesn't seem to be having the same effect. Can antidepressants lose effectiveness? Answer From Daniel K. Identification and treatment of antidepressant tachyphylaxis. Innovations in Clinical Neuroscience. Israel "Will" of Psychiatry and Related Sciences. El-Mallakh RS, et al. The role work what will long term antidepressant use in inducing chronic depression.

Thase M, et al. Unipolar treatment resistant depression in adults: Epidemiology, risk factors, assessment, and prognosis. Accessed March 17, Fava GA, et al. The mechanisms of tolerance in antidepressant action. Rational use of antidepressant drugs. Maust DT, et al. Going beyond antidepressant monotherapy for incomplete response in non-psychotic late-life depression: American Journal of Geriatric Psychiatry.

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