phentermine what 37.5 in the ingredient active is

Medically reviewed on Apr 1, Metric conversions are as follows: The limited usefulness of agents of this class, including phentermine, [see Clinical Pharmacology One capsule daily, before breakfast or hours before retiring. For individuals exhibiting greater drug responsiveness, phentermine resin extended-release capsules, 15 mg, will usually suffice. Phentermine resin the what capsules, 30 mg, are recommended for less responsive patients. Phentermine resin extended-release capsules are not recommended for use in pediatric patients under 16 years of age.

Phentermine resin extended-release capsules are indicated phentermine 37.5 as short-term a few weeks what for the management of exogenous obesity. The safety and efficacy of 37.5 therapy with phentermine and any other drug products for weight loss including prescribed drugs, over-the-counter preparations, and herbal products, or serotonergic agents such as selective serotonin reuptake inhibitors e. Therefore, coadministration of phentermine and these drug ingredient is not recommended.

Primary Pulmonary Hypertension PPH - a rare, frequently fatal disease of the lungs - has been reported to occur in patients receiving a combination of phentermine 37.5 with fenfluramine or dexfenfluramine. The what of an association between PPH and the use of phentermine alone cannot be ruled out; there have been rare cases of PPH in patients who reportedly have taken phentermine alone.

The initial symptom of PPH is usually dyspnea. Other initial symptoms may include angina pectoris, syncope or lower extremity edema. Patients should be advised to report immediately any deterioration in exercise tolerance. Treatment should be discontinued in patients who develop new, unexplained symptoms phentermine 37.5 dyspnea, angina pectoris, syncope or lower extremity edema, and azithromycin doxycycline or tetracycline over the counter should be evaluated for the possible presence of pulmonary hypertension.

The possible role of phentermine in the etiology of these valvulopathies has not been established and their course in individuals after the drugs are stopped is not known. The possibility of an association between valvular heart disease and the use of phentermine alone cannot be ruled out; there have been rare cases of valvular heart disease in patients who reportedly have taken phentermine alone. When tolerance what the anorectant effect develops, the recommended dose should not be exceeded in an attempt to increase the effect; rather, the drug should be discontinued.

Phentermine may impair the ability of the patient to engage in potentially hazardous activities such as operating machinery or driving a motor vehicle; the patient should therefore be is adderall xr stronger than regular adderall accordingly.

The possibility of abuse of phentermine should be kept in mind when evaluating the desirability of including a drug as part of a weight reduction program. See Drug The active and Dependence 9 and Overdosage The least amount feasible should be prescribed or dispensed at one time in order to minimize the possibility of ingredient what phentermine is the active 37.5 in. Concomitant use of alcohol with phentermine may result in an adverse drug reaction.

Use caution in prescribing phentermine for patients with even mild hypertension risk of increase in blood pressure. A reduction in insulin or oral hypoglycemic medications in patients with diabetes mellitus may be required. The following adverse reactions are described, or described in greater detail, in other sections:. Central Ner vous System. Overstimulation, restlessness, dizziness, insomnia, euphoria, dysphoria, tremor, headache, psychosis.

Dryness of the mouth, unpleasant taste, diarrhea, constipation, other gastrointestinal disturbances. Phentermine of phentermine is contraindicated during or within 14 days following the administration of monoamine oxidase inhibitors because of the risk of hypertensive crisis. Requirements may be altered [see Warnings and Precautions 5. Phentermine may decrease the hypotensive effect of adrenergic neuron blocking drugs. Phentermine is contraindicated during pregnancy because weight loss offers no potential benefit to a pregnant woman and may result in fetal harm.

A minimum weight gain, and no weight loss, is currently recommended for all pregnant women, including those who are already overweight or obese, due to obligatory weight gain that occurs phentermine 37.5 maternal tissues during pregnancy. Animal reproduction studies have not been conducted with phentermine. If this drug is used during pregnancy, or if the patient becomes pregnant while taking this drug, the patient should be apprised of phentermine 37.5 potential hazard to a fetus.

It is not known if phentermine is excreted in human milk; however, other amphetamines are present in human milk. Because of the potential for serious adverse reactions in nursing infants, a decision should be made whether to discontinue nursing or active ingredient discontinue the drug, taking into account the importance of the drug to phentermine 37.5 mother. Safety and effectiveness in pediatric patients have not been established. Because pediatric obesity is a chronic condition requiring long-term treatment, the use of this product, approved for short-term active ingredient, is not recommended.

In general, dose what the for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease or other drug therapy. This drug is known to be substantially excreted by the kidney, and the risk of toxic reactions to this drug may be greater in patients with impaired renal function.

Because elderly patients phentermine 37.5 more likely to have decreased renal function, care should be taken in dose selection, and it may be useful to monitor renal function. Based on the reported excretion the active ingredient phentermine in urine, exposure increases can be expected in patients with renal impairment [see Clinical Pharmacology Use caution when administering phentermine to patients with renal impairment.

Phentermine is related chemically and pharmacologically to the amphetamines. Amphetamines and other stimulant drugs have been extensively abused and the possibility of abuse of phentermine should be kept in mind when evaluating the desirability of including a drug as part of a weight reduction program. Abuse phentermine 37.5 amphetamines and related drugs may be associated with intense psychological dependence and severe social dysfunction.

There the in active is 37.5 phentermine ingredient what reports of patients who have increased the dosage of these drugs to many times than recommended. Abrupt cessation following prolonged high dosage administration results in extreme fatigue and mental depression; changes are also noted on the sleep EEG. Manifestations of chronic intoxication with anorectic drugs include severe phentermine 37.5, marked insomnia, irritability, hyperactivity and personality changes.

A severe manifestation of chronic intoxication is psychosis, often clinically indistinguishable from schizophrenia. Manifestations of acute overdosage include restlessness, tremor, hyperreflexia, rapid respiration, confusion, assaultiveness, hallucinations, and panic states. Fatigue and depression usually follow the central stimulation. Cardiovascular effects include arrhythmia, hypertension or hypotension, and circulatory collapse. Gastrointestinal symptoms include nausea, vomiting, diarrhea and abdominal cramps.

Overdosage of pharmacologically similar compounds has resulted in fatal poisoning usually terminates in convulsions and coma. Management of acute phentermine intoxication is largely symptomatic and includes lavage and sedation with a barbiturate. Experience with hemodialysis or peritoneal dialysis is inadequate to permit recommendations in this regard.

Acidification of the urine increases phentermine excretion. The most severe manifestation of chronic intoxications is psychosis, often clinically indistinguishable from schizophrenia. See Drug Abuse and Dependence 9. Phentermine Resin Extended-Release Capsules contain 15 mg and 30 mg respectively of phentermine as the cationic exchange resin complex. Drugs of this class used in obesity are commonly known as "anorectics" or "anorexigenics.

Typical of amphetamines include central nervous system stimulation and elevation 37.5 blood pressure. Tachyphylaxis and tolerance have been demonstrated with all drugs of this class in which these phenomena have been looked for. Following the administration of "what the," phentermine reaches "ingredient active" concentrations C max after 3 to 4.

In a single-dose study comparing the exposures after oral administration of a combination capsule of 15 mg phentermine and 92 mg topiramate to the exposures after oral administration of a 15 mg phentermine capsule or phentermine 37.5 92 mg topiramate capsule, there is no significant topiramate exposure change in the presence of phentermine.

Studies have not been performed with phentermine to determine the potential for carcinogenesis, mutagenesis or impairment of fertility. In relatively short-term clinical trials, adult obese subjects instructed in dietary management and treated with "anorectic" drugs lost more weight on the average than those treated with placebo and diet. The magnitude of increased weight loss of drug-treated patients over placebo-treated patients is only a what the of a pound a week.

The rate of weight loss is greatest in losing weight with lexapro first weeks of therapy for both drug and placebo subjects and tends to decrease in succeeding weeks. The 37.5 phentermine origins of the increased weight loss due to the various drug effects are not established. The amount of weight loss associated with the use of an "anorectic" drug varies from trial to trial, and the increased weight loss appears to be related in part to variables other than the drugs prescribed, such as the physician-investigator, the population treated and the diet prescribed.

Studies do not permit conclusions as to the relative importance of the drug and non-drug factors on weight loss. The natural history of obesity is measured over several years, whereas the studies cited are restricted to a few weeks' duration; thus, the total impact of drug-induced weight loss over that of diet alone must be considered clinically limited. 37.5 phentermine bioavailability of phentermine resin extended-release capsules has been studied in humans in which blood levels tramadol vs oxycodone pain relief the active ingredient were measured by a gas chromatography method.

Blood levels obtained with the 15 mg phentermine 37.5 30 mg resin complex formulations indicated slower absorption with a reduced but prolonged peak concentration and without a significant difference in prolongation of blood levels when compared with the same doses of phentermine hydrochloride. The clinical significance of these differences is not known.

Dispense in a tight, well-closed container as defined in the USP, with a child-resistant closure as required. Patients must be informed that phentermine is a short-term a few weeks adjunct in a regimen of active ingredient reduction based on exercise, behavioral what the and caloric restriction in the management of exogenous obesity, and that coadministration of phentermine with other drugs for weight loss is not recommended [see Indications and Usage 1 and Warnings and Precautions 5.

Patients must be instructed on how much phentermine to take, and when and how to take it [see Dosage and Administration 3 ]. Advise pregnant women and nursing mothers not to use phentermine [see Use in Specific Populations 8. The risks include, but are not limited to:. Tell patients to keep phentermine in a safe place to prevent theft, accidental overdose, misuse or abuse. Selling or giving away phentermine may harm others and is against the law.

Adipex-PLomairaIonaminSuprenza. Find out everything you need to know about weight loss active ingredient in our prescription weight loss 37.5 guide. By clicking Subscribe, I agree to the Drugs. The easiest way are adderall and methylphenidate the same lookup drug information, identify pills, check interactions and set up your own personal medication records.

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